Role of extracorporeal shock wave therapy in management of Peyronie’s disease: A preliminary report
Introduction: Peyronie’s Disease (PD) is a disease causing psycho social trauma to the patient. Multiple
treatment options are available with variable results. Extra Corporeal Shock Wave Therapy (ESWT) is a new
insight into the non invasive modality of management. It focuses on the mechanism of inducing angiogenesis
in the penile cavernous tissue.
Materials and Methods: The aim of the study is to determine the role of ESWT in the management of PD.
The objectives include demonstrating the improvement in mean International Index of Erectile Function
Score (IIEFS), improvement in pain score by Visual Analogue Scale (VAS), change in cavernosal artery flow
on colour penile Doppler, reduction in plaque size, and improvement in penile curvature degree after the
therapy. 30 patients, between 25-65 years, who were non responders to conservative line of management,
were treated with ESWT. The results were evaluated at baseline and 18-24 weeks after the therapy.
Results: ESWT significantly improves the cavernosal artery velocity, thereby supporting the theory of
angiogenesis. ESWT improves all the domains of IIEF including Erectile Function, Sexual Desire, Sexual
Satisfaction, Orgasm and Overall Satisfaction. There is a significant improvement in the pain and penile
curvature, and reduction in the plaque size. No adverse effects have been recorded.
Conclusion: ESWT offers a safe, minimally invasive, OPD based option to the management of the patients of
PD in the stable phase of the disease. Patients who do not respond to the conservative line of management
can be really benefited by ESWT.
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