Multimodality imaging of myocardial revascularization using cardiac shock wave therapy

G. Zuoziene, D. Leibowitz, J. Celutkiene, G. Burneikaite, L. Ivaskeviciene, G. Kalinauskas, V.V. Maneikiene, D. Palionis, V. Janusauskas, N. Valeviciene, A. Laucevicius
International Journal of Cardiology 187 (2015) 229–230

Ischemic heart disease remains a leading cause of morbidity and mortality worldwide. Despite modern therapies, many patients still suffer from refractory angina pectoris (RAP) therefore, alternative non-invasive revascularization methods are under development. One of the methods stimulating angiogenesis is cardiac shock wave therapy (CSWT), a new treatment method offering an alternative to revascularization. Recent studies have demonstrated that the extracorporeal application of low-intensity shockwaves to the myocardium may induce the release of angiogenesis-mediating growth factors such as endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF), as well as induce the recruitment of endothelial progenitor cells [1–4].

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